Novel Regenerative Concepts Using NovoMatrix an acellular dermal matrix
Dr. Gerhard Iglhaut
NovoMatrix™ is an acellular dermal matrix derived from porcine tissue. In surgical application, the tear-resistant and easy-to-handle1, 2 matrix is an excellent alternative to autologous connective tissue grafts (CTG). There is no need for an intraoral surgical donor site, which reduces morbidity for the patient.
Owing to the manufacturing process, the matrix is free of donor cells. At the same time, the structure of the source tissue remains virtually unchanged, thus supporting the ingrowth of cells and micro-vessels. Proprietary tissue processing enables optimal cell repopulation and revascularization through gentle preparation, resulting in esthetic soft tissue regeneration.3 NovoMatrix™ is supplied pre-hydrated in a patented aqueous phosphate-buffered solution containing matrix stabilizers and can therefore be used promptly without requiring extensive rehydration.4
Recession coverage – tunnel technique
General alveolar ridge augmentation
Tissue thickening around implants and teeth employing the pouch technique
Maintenance of graft integrity is essential to achieving successful biological outcomes. NovoMatrix™ is minimally manipulated and processed gently to ensure it retains components critical to maintaining the biochemical and biomechanical integrity of the tissue.
Triple-stranded proteins that assemble into fibril complexes to provide structure and tensile strength5
Fibers that function in close association with collagen to provide elasticity and recoil5
High molecullar weight polysaccharide molecules that control tissue hydration, driving water transport and maintaining the elastoviscosity of connective tissues throughout the body5
Large and small macromolecules which guide revascularization and cell repopulation and regulate extracellular matrix structure through assembly and construction6
Complex proteins that mediate a variety of cellular interactions; responsible for modulating cell adhesion, migration, growth, and differentiation7
Vessels which provide blood flow trhoughout the matrix, enabling initial revascularization8
Get to know different surgical techniques when using NovoMatrix™ and let the experienced speakers explain the possibilities of and with NovoMatrix™ to you.To the NovoMatrix courses →
Time: 58 min
Time: 93 min
Time: 70 min
For over two decades LifeCell™ has been developing innovative products for a wide range of applications. With over 2.5 million grafts to date, 25 years of experience in tissue processing and an ongoing commitment to innovation, LifeCell™ has joined forces with BioHorizons and Camlog to bring NovoMatrix™, the next generation soft-tissue augmentation material to dentistry.
Foundation of the LifeCell™ Corporation
BioHorizons begins distribution of AlloDerm™ RTM for dentistry (U.S.)
AlloDerm™ RTM for guided bone regeneration (U.S.)
NovoMatrix™ Reconstructive Tissue Matrix for applications in dentistry (EU)*
*NovoMatrix™ is cleared for sale in the European Union.
Manufactured from targeted porcine tissue for desired mechanical and handling properties.
Non-chemical based method that removes all non-dermal tissue retaining the structural integrity of the matrix.
Proprietary process removes 99.9 % of the pathogens, enabling a more gentle preparation process.
Maintains the natural collagen structure while extracting the porcine alpha-gal antigen, as well as the cell and DNA components to minimize the xenogenic immune response.
The proprietary preparation process stabilizes the key matrix proteins as well as protecting the integrity of the acellular dermal matrix, thus providing a platform for tissue regeneration.
Optimized sterilization process to preserve the natural tissue structure, thus retaining the regenerative properties of the acellular dermal matrix.
An intact acellular dermal matrix derived from porcine tissue that retains the biochemical components that support a positive immunological response and regeneration.12, 16, 17
NovoMatrix™ shows a histological structure comparable to human tissue.12, 16, 17
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